Spain's goalkeeper Iker Casillas (R) hugs David Villa after the 2010 World Cup second round soccer match between Spain and Portugal at Green Point stadium in Cape Town June 29, 2010. [Agencies]

Portugal's Cristiano Ronaldo reacts with dejection as he walks off the pitch after the 2010 World Cup second round soccer match against Spain at Green Point stadium in Cape Town June 29, 2010. [Agencies]

Spain continued to dominate possession after the break but struggled to find a way through until Del Bosque's inspired substitution after 58 minutes.

A weary-looking Torres gave way to Fernando Llorente and two minutes later the big striker forced Casillas into a great save with his first touch - a diving header.

His presence upset Portugal's concentration and spurred Spain to accelerate their approach.

It paid off decisively in the 63rd minute when after another crisp move from deep, Xavi cleverly rolled Andres Iniesta's pass into the path of Villa and though the forward's left-foot shot was saved he reacted quickly to ram in the rebound with his right for his fourth goal of the tournament.

Sergio Ramos, Villa and Llorente all went close to a second, with Eduardo keeping his side clinging on.

But in reality Portugal, semi-finalists four years ago, were going out of the tournament and like a leaf in a whirlpool there was absolutely nothing they could do about it as Spain's incomparable possession play deprived them of the ball.

Portugal's disappointing night was completed with a harsh red card for Ricardo Costa after a mild off-the-ball clash with Joan Capdevila but Spain march on.

"It was a great collective effort, we tied to keep possession, keep the style of football we've been playing," said man of the match midfielder Xavi.

"I think this is the best match we've played in this World Cup."