国产热热热精品,亚洲视频久久】日韩,三级婷婷在线久久,99人妻精品视频,精品九热人人肉肉在线,AV东京热一区二区,91po在线视频观看,久久激情宗合,青青草黄色手机视频

USEUROPEAFRICAASIA 中文雙語Fran?ais
Lifestyle
Home / Lifestyle / Health

Scientists explain why farm children less likely to have asthma

Xinhua | Updated: 2015-09-06 18:31

A European team on Thursday proposed a new explanation for why children growing up on farms are far better protected against asthma and allergies.

The protective effect may be created by a particular anti-inflammatory protein called A20, which the body produces upon contact with farm dust, according to the team, led by researchers from Belgium's Flanders Institute for Biotechnology (VIB) and Ghent University.

The findings, published in the leading journal Science, may represent a major step forward towards the development of an asthma vaccine.

For the study, the researchers first exposed mice to farm dust extract, a bacterial component called endotoxin, every other day for two weeks.

They then presented these mice with allergy-driving house dust mites, which often cause asthma in people, finding that mice that had been regularly exposed to endotoxin did not develop allergic features, while control mice did.

Further research found that endotoxin exposure appears to have protected the mice by squashing the ability of the animals'lung epithelial cells to generate pro-inflammatory molecules, but this protective effect only worked in the presence of the A20 protein.

"When we inactivate the A20 protein in the mucous membrane of the lungs, farm dust is no longer able to reduce an allergic or asthmatic reaction," study author Professor Hamida Hammad of VIB and Ghent University said.

These findings were then tested in patients. The results showed that people suffering from allergies and asthma have a deficiency in the protective protein A20, explaining why they react to allergens so severely.

"Discovering how farm dust provides this type of protection has certainly put us on the right track towards developing an asthma vaccine and new allergy therapies," Hammad said. "However, several years of research are required still before they will be available to patients."

Some experts cautioned that the newly uncovered mechanism does not entirely explain the protective effect of farm life.

For example, it is commonly known that drinking raw cow's milk can provide protection against allergies, but that effect is unlikely to involve the lung epithelium, Gary Huffnagle of the University of Michigan, Ann Arbor, told Science.

Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US
东海县| 阿荣旗| 漳浦县| 峡江县| 孝义市| 六枝特区| 马山县| 通化市| 祁连县| 东兰县| 霍山县| 普兰县| 婺源县| 商南县| 邵武市| 嵩明县| 侯马市| 阳西县| 大庆市| 米林县| 讷河市| 湘阴县| 台湾省| 高州市| 湟中县| 晋中市| 孟津县| 黄平县| 井陉县| 聊城市| 八宿县| 麻阳| 上虞市| 万州区| 南涧| 垦利县| 海南省| 绥德县| 肃宁县| 宁波市| 平阴县|